Design and rationale of a prospective longitudinal cohort study corresponding author. Pathways from childhood selfregulation to cardiovascular risk in adolescence article pdf available in bmc public health 161. We aimed to investigate the effect of four different physical activity coaching interventions on daily step count in a substudy of the myheart counts study. Objective to characterize patterns of findings on cranial magnetic resonance imaging mri of the elderly using a statistical technique called cluster analysis subjects and methods the cardiovascular health study is a populationbased, longitudinal study of 5888 people 65 years and older. Objectives we sought to characterize the predictors of incident congestive heart failure chf, as determined by central adjudication, in a communitybased elderly population. Study design collection american journal of epidemiology. Low serum uromodulin sumod levels are associated with mortality and cardiovascular disease.
Abu mohd naser, emory university leanne unicomb, international centre for diarrhoeal disease research, solaiman doza, international centre for diarrhoeal disease research. The cardiovascular health study sponsored by the national heart, lung and blood institute the cardiovascular health study chs is an nhlbifunded observational study of risk factors for cardiovascular disease in adults 65 years or older. The coacs study is a communitybased, prospective study, to investigate how suboptimal health status contributes to the incidence of ncd in chinese adults. The overall objective of the international collaborative study of cardiovascular disease in asia interasia was to estimate the prevalence and distribution of cardiovascular disease risk factors. Polypill for the prevention of cardiovascular disease polyiran. Polypill for the prevention of cardiovascular disease. Steppedwedge clusterrandomised controlled trial to. The medirivage study mediterranean diet, cardiovascular. Chs is designed to determine the importance of conventional cardiovascular disease cvd risk factors in older adults, and to identify new risk factors in this age. Read the original article in full on wellcome open research. Design and rationale abstract the cardiovascular health study chs is a populationbased, longitudinal study of coronary heart disease and stroke in adults aged 65 years and older. Health and text messaging chat study and the chatdiabetes mellitus chat.
The myheart counts cardiovascular health study is a longitudinal smartphonebased study with the aim of elucidating the determinants of cardiovascular health. The cardiovascular health study chs is a populationbased, longitudinal study of coronary heart disease and stroke in adults aged 65 years and older. Cardiovascular risk factors and incident acute renal. Global heart is the official and primary publication of the world heart federation, offering a platform for the dissemination of knowledge on research, developments, trends, solutions and public health programmes in the area of cardiovascular disease. Design and rationale for a pragmatic cluster randomized. The chs cardiovascular health study prospectively enrolled. The medirivage study mediterranean diet, cardiovascular risks and gene polymorphisms. In 2016, the journal introduced a new section entitled study design.
Pdf steppedwedge clusterrandomised controlled trial to. Task shifting of frontline community health workers for. Our study is the largest community based cluster randomised trial in low and middleincome country settings designed to test the effectiveness of task shifting interventions involving frontline health workers for cardiovascular risk reduction. Background the elderly constitute a growing proportion of patients admitted to the hospital with chf, and chf is a leading source of morbidity and mortality in this group. Study of cardiovascular health outcomes in the era of claims data. Rationale, study design and implementation of the colm. Design and rationale, abstract the cardiovascular health study chs is a populationbased, longitudinal study of coronary heart disease and stroke in adults aged 65 years and older. The aim is to describe the rationale, study design, and first results of the dutch risk or benefit in screening for cardiovascular disease robinsca trial, the first populationbased randomisedcontrolled computedtomography screening trial for cardiovascular disease, powered to detect a benefit of 15% reduced chdmorbidity and mortality. Starting in 1989, and continuing through 1999, participants underwent annual extensive clinical examinations. Design and rationale in this communication we describe the objectives and the design of the cardiovascular health study. Plasma ceramides and sphingomyelins in relation to atrial.
Design and rationale of the cardiovascular health and. Pdf the sleep heart health study shhs is a prospective cohort study designed to investigate obstructive sleep apnea osa and other sleepdisordered. Among 4206 chs cardiovascular health study participants mean age, 76 years. Methods and resultsdata from the cardiovascular health study. Uromodulin is released by tubular epithelial cells into the serum and lower levels are associated with more severe interstitial fibrosis and tubular atrophy. Timi study group, cardiovascular division, department. Data from the cumulative psychological stress study in middleaged and older women study within the womens health study is expected to provide clinically valuable information regarding the interaction of acute and chronic stressors with lifestyle, environmental and genetic influences on.
Design and rationale of the edoxaban treatment in routine. To determine the disease, functional, and personal characteristics that jointly predict mortality. The second manifestations of arterial disease smart study is a singlecentre prospective cohort study among patients, newly referred to the hospital with 1 clinically manifest atherosclerotic vessel disease, or 2 marked risk factors for atherosclerosis. Of these, 3230 underwent cranial mri scans, which were coded for presence of infarcts and grades for. Predictors of congestive heart failure in the elderly. The main objective of the study is to identify factors related to the onset and course of coronary heart disease and stroke. The 2,962 women and 2,239 men were examined yearly from 1989 through 1999. Rationale, design and conduct of a crosssectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 3569 years from two russian cities, 201518. The first objectives of the smart study are to determine the prevalence of concomitant arterial disease at other sites, and risk. Cardiovascular riskprofile imaging and genderspecific disorders crewimago.
This paper describes the research design and the rationale of the study. In southwest coastal bangladesh, communities have few options but to. Besides being an operational manual for surveys, it provides. There is strong evidence of effectiveness for interventions that engage community health workers in a teambased care model to improve blood pressure and cholesterol in patients at increased risk for cvd. Nterminal probtype natriuretic peptide is associated. The sleep heart health study shhs is a prospective cohort study designed.
Here we present the rationale and design of save bc. The cardiovascular health study sponsored by the national heart, lung and blood institute. More information about the rationale, design, and protocol of the shhs study can be found in the dedicated nsrr section 41, and in the related literature 42, 43. Pdf international collaborative study of cardiovascular. The cardiovascular health study chs, a longitudinal study of older men and women, is an ideal population in which to assess the association between levels of amino terminal pro btype natriuretic peptide ntprobnp and scd in a large, biracial cohort. Prof lixin jiang, national clinical research center of cardiovascular diseases, state key laboratory of cardiovascular disease, fuwai hospital, national center for cardiovascular. Reduction of cardiovascular events with icosapent ethylintervention trial. Pdf rationale, design and methods for the right track. Cardiovascular health study 1,350 participants, framingham heart study 1,000 participants, strong heart study 600 participants, new york hypertension cohorts 1,000 participants, and tucson epidemiologic study of airways obstructive diseases and the health and environment.
Methodsdesign the simcard study is a clusterrandomized controlled interventional trial to be conducted in rural areas of. However, little is known about the association of sumod levels with longterm kidney outcomes in older adults, a population with a high. A clusterrandomized controlled trial to evaluate the. Cardiovascular survey methods world health organization. The associations of cardiovascular disease risk factors, subclinical cardiovascular disease, and clinical coronary heart disease with the risk for development of acute renal failure were examined in older adults in the cardiovascular health study, a prospective cohort study of communitydwelling.
Prevention of cardiovascular disease who world health. Participants in shhs were recruited from nine existing nhlbi epidemiological studies in which data on cardiovascular risk factors had been collected previously. Global heart welcomes research results, points of view and educational material on the prevention, treatment and control of cardiovascular. Cardiovascular riskprofile imaging and genderspecific. Second manifestations of arterial disease smart study. The cardiovascular health study chs is a study of risk factors for development and progression of chd and stroke in people aged 65 years and older. The community preventive services task force recommends interventions that engage community health workers to prevent cardiovascular disease cvd.
Saltwater intrusion and salinisation have contributed to drinking water scarcity in many coastal regions globally, leading to dependence on alternative sources for water supply. Office of health promotion and disease prevention, department of medicine, emory university school of medicine, atlanta, georgia. The effect of digital physical activity interventions on. Risk factors for cardiovascular disease across the spectrum of older age.
Epidemiologic study designs epidemiology learning materials. Rationale, design and methods for the right track health study. The cardiovascular health study chs is an nhlbifunded observational study of risk factors for cardiovascular disease in adults 65 years or older. Pdf the sleep heart health study shhs is a prospective cohort study designed to investigate obstructive sleep apnea osa and other sleep disordered. In 20, a study of 17 countries showed that the prevalence, awareness, and control of hypertension. Details on specific methods are available in the chs manuals of operation 11.
Multiple factors contribute to mortality in older adults, but the extent to which subclinical disease and other factors contribute independently to mortality risk is not known. Design and rationale of the tobacco, exercise and diet messages text me trial of a text messagebased intervention for ongoing prevention of cardiovascular disease in people with coronary disease. Risk or benefit in screening for cardiovascular disease. Design and rationale of the cardiovascular health and text messaging chat study and the chatdiabetes mellitus chatdm study. Hypertension is a global public health challenge and a major modifiable risk factor of cardiovascular disease cvd and premature death. A comprehensive description of the methods used in the study is contained in the shhs manual of op erations 9. Rationale, study design and implementation of the colm study. There are innumerable decisions, judgments, and compromises that must be made during the design, conduct, analysis, and interpretation of a study, and the principal guideposts for making them are the study objectives and rationale. Participants can potentially benefit from information obtained in this study concerning their current cardiovascular health and expected future risk of cardiovascular events. Design, rationale, and methods article pdf available in sleep 2012.
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